CB2 rabbit pAb
ENT-A2337
Description
| REF | ENT-A2337 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CB2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CNR2. AA range:191-240 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 33kD |
| Human Gene ID | 1269 |
| Human Swiss Prot Nº | P34972 |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, dendrite . Perikaryon . Localizes to apical dendrite of pyramidal neurons. . |
Other Name: CNR2; Cannabinoid receptor 2; CB-2; CB2; hCB2; CX5
Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008],