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AIFL rabbit pAb

AIFL rabbit pAb

ENT-A2114

Description

 

 

 

REF ENT-A2114
Category Antibody Polyclonal
Description AIFL rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 67kD
Human Gene ID 150209
Human Swiss Prot Nº Q96NN9
Subcellular Location Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis.

Other Name: AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein

Background: domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,