ABCC12 rabbit pAb
ENT-A2066
Description
| REF | ENT-A2066 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ABCC12 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRP9. AA range:691-740 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 170kD |
| Human Gene ID | 94160 |
| Human Swiss Prot Nº | Q96J65 |
| Subcellular Location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
Other Name: ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12
Background: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008],