JAK1 (phospho Tyr1022) rabbit pAb
ENT-A1855
Description
| REF | ENT-A1855 |
|---|---|
| Category | Antibody Polyclonal |
| Description | JAK1 (phospho Tyr1022) rabbit pAb |
| Source | Rabbit |
| Applications | IF;WB;IP;IHC;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IF: 1:50-200 Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 132kD |
| Human Gene ID | 3716 |
| Human Swiss Prot Nº | P23458 |
| Subcellular Location | Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated. |
Other Name: JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Background: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],