CRM1 (Acetyl Lys568) rabbit pAb
ENT-A1756
Description
| REF | ENT-A1756 |
|---|---|
| Category | Antibody Polyclonal |
| Description | CRM1 (Acetyl Lys568) rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 125kD |
| Human Gene ID | 7514 |
| Human Swiss Prot Nº | O14980 |
| Subcellular Location | Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm. |
Other Name: XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],