ATG13 Rabbit pAb
ENT-A1372
Description
| REF | ENT-A1372 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ATG13 Rabbit pAb |
| Source | Rabbit |
| Applications | IHC |
| Reactivity | Human, Mouse, Rat |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 57kDa |
| Human Gene ID | 9776 |
| Human Swiss Prot Nº | O75143 |
| Subcellular Location | Cytoplasm |
Other Name: KIAA0652, Apg13,Autophagy-related protein 13 antibody
Background: Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.