IκB α Rabbit pAb
ENT-A1246
Description
| REF | ENT-A1246 |
|---|---|
| Category | Antibody Polyclonal |
| Description | IκB α Rabbit pAb |
| Source | Rabbit |
| Applications | WB, IHC |
| Reactivity | Human, Rat |
| Reactivity | Human, Rat |
| Dilution | WB 1:2,000-5,000 IHC 1:200-500 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 40kDa |
| Human Gene ID | 4792 |
| Human Swiss Prot Nº | P25963 |
| Subcellular Location | Cytoplasm,Nucleus |
Other Name: I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.