ATG7 (3D6) Mouse mAb
ENT-A1624
Description
| Ref | ENT-A1624 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | APG7, GSA7, Autophagy related protein 7 |
| Application | IHC |
| Source | Mouse |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 78kDa |
| Human Gene ID | 10533 |
| Human Swiss Prot No | O95352 |
| Subcellular Location | Cytoplasm |
Background: The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.