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ATM (1D1) Mouse mAb

ATM (1D1) Mouse mAb

ENT-A1606

Description

Ref ENT-A1606
Category Antibody Monoclonal
Alternative Name AT1,ATA,ATDC,TEL1,A-T mutated antibody
Application IHC
Source Mouse
Reactivity Human, Rat, Mouse
Dilution IHC 1:100-200
Immunogen Recombinant Protein
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 350kDa
Human Gene ID 472
Human Swiss Prot No Q13315
Subcellular Location Cytoplasmic vesicle, Nucleus

Background: Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair. ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair.