Phospho-Akt (S473) (6F8) Mouse mAb
ENT-A1578
Description
| Ref | ENT-A1578 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | c Akt antibody, MGC9965 antibody, Protein kinase B antibody, RAC antibody, PRKBA antibody |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 60kDa |
| Human Gene ID | 207 |
| Human Swiss Prot No | P31749 |
| Subcellular Location | Cytoplasm,Nucleus,Cell membrane |
Background: Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration. Akt1 is involved in cellular survival pathways, by inhibiting apoptotic processes. Akt1 is also able to induce protein synthesis pathways, and is therefore a key signaling protein in the cellular pathways that lead to skeletal muscle hypertrophy, and general tissue growth.