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P53(Mono Methyl Lys370) Mouse mAb

P53(Mono Methyl Lys370) Mouse mAb

ENT-A1547

Description

Ref ENT-A1547
Category Antibody Monoclonal
Alternative Name Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
Application IHC
Source Mouse
Reactivity Human, Rat, Mouse
Dilution IHC  1;500-1,000
Immunogen Synthetic Peptide
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 53kDa
Human Gene ID 7157
Human Swiss Prot No P04637
Subcellular Location Cytoplasm,Cytoplasm. Nucleus

Background: p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.