Caspase 8 Mouse mAb
ENT-A1529
Description
| Ref | ENT-A1529 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | ALPS2B antibody, Apoptosis cysteine protease antibody, CAP4 antibody, CED3 antibody, MCH5 antibody |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 43,57kDa |
| Human Gene ID | 841 |
| Human Swiss Prot No | Q14790 |
| Subcellular Location | Cytoplasm |
Background: Caspase-8 is a caspase protein, encoded by the CASP8 gene. It most likely acts upon caspase-3. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7.