AMACR/P504S Mouse mAb
ENT-A1427
Description
| Ref | ENT-A1427 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | Alpha-Methylacyl Coenzyme A Racemase ;RACE; 2-methylacyl-CoA racemase |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000 IHC 1:200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 42kDa |
| Human Gene ID | 23600 |
| Human Swiss Prot No | Q9UHK6 |
| Subcellular Location | Peroxisome. Mitochondrion |
Background: AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.