Histone H3 Mouse mAb
ENT-A1417
Description
| Ref | ENT-A1417 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody |
| Application | WB, IHC, IF, IP |
| Source | Mouse |
| Reactivity | Human, Mouse, Rat, Yeast |
| Dilution | WB 1:2,000-5,000 IP 1:200 IF 1:200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 15kDa |
| Human Gene ID | 8290 |
| Human Swiss Prot No | P68431 |
| Subcellular Location | Nucleus,Chromosome |
Background: Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.